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AACR 2011: Blood test for lung cancer in never-smokers
Dr Charlie Birse - Celera Corporation, California, USA A panel of biomarkers appears to be able to identify the presence of lung cancer in the blood samples of people who have never smoked. While lung cancer has long been linked to smoking, approximately one-quarter of patients with lung cancer have never smoked. Dr Charlie Birse and colleagues are investigating the potential for a serum test that would examine the reliability of a proprietary panel of biomarkers for lung cancer. The goal is to...
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Time : 2 min 36
Added : 26/05/11 16:13
Tags: blood tests for lung cancer / about lung cancer from smoking / lung cancer stage
AACR 2011: New target identified for squamous cell lung cancer
Prof Matthew Meyerson - Dana Farber Cancer Institute, Boston, United States. Scientists at the Dana Farber Cancer Institute have identified a mutation in the DDR2 gene that may indicate which patients with squamous cell lung cancer will respond to dasatinib. There are currently no targeted therapies for squamous cell lung cancer, a disease which accounts for 30% of all non-small cell lung cancers. Using standard genetic sequencing techniques, Prof Matthew Meyerson and colleagues identified...
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Time : 7 min 34
Added : 27/05/11 11:11
Tags: non small cell squamous lung cancer / non small cell lung cancer treatment / small cell lung cancer treatments
EMCTO 2011: Staging procedures for non-small cell lung cancer
Prof Johan Vansteenkiste, Universitair Ziekenhuis, Belgium, talks about staging procedures for patients with non-small cell lung cancer (NSCLC) and explains that for most patients a combination of imaging with PET and CT scans followed by endoscopic ultrasound is sufficient; however some patients will also require a surgical procedure to verify results. Prof Vansteenkiste outlines the key stages for patients, explains how this improved understanding of the patients' condition allows clinicians...
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Time : 8 min 25
Added : 15/03/11 10:41
Tags: non small cell lung cancer stage / non small cell lung cancer treatment options / small cell lung cancer treatments
EMCTO 2011: Role of predictive markers in personalised cancer treatment
Prof Ken O'Byrne, St James's Hospital, Dublin, Ireland, discusses the role of pathology in determining the best treatment options for non-small cell lung cancer patients. Clinicians use molecular characteristics of tumours to decide on the optimal treatment for each patient and this personalised approach is associated with an improved response rate. Prof O'Byrne explains when patients would undergo these tests, talks about the difficulties encountered using these tests to decide upon the best...
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Time : 11 min 34
Added : 15/03/11 10:05
Tags: non small cell lung cancer treatment options / small cell lung cancer treatments / best hospital for lung cancer treatment
EMCTO 2011: Treatment options for low grade neuroendocrine lung carcinoma
Dr Martin Frueh, Kantonsspital, St Gallen, Switzerland, talks about low grade neuroendocrine lung carcinoma and emphasises the need for more research to be carried out to improve our understanding of this very rare disorder. Although there has been a considerable amount of research into targeted treatments for small cell lung cancer, these studies have not been particularly successful. Dr Frueh discusses the need for a better understanding of the complex biology behind this disease and for the...
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Time : 8 min 36
Added : 15/03/11 09:46
Tags: lung cancer small cell carcinoma / small cell lung cancer treatments / lung cancer treatment options
EMCTO 2011: Stereotactic radiosurgery for stage I non-small cell lung cancer
Dr Rafael Dziadziuszko, Medical University of Gdansk, Poland, talks about stereotactic radiosurgery for stage I non-small cell lung cancer. This technology allows clinicians to accurately deliver high doses of radiation to cancerous areas of the lung with minimal disturbance to healthy tissues. Although the procedure is primarily used for medically inoperable patients, it is associated with excellent local control rates similar to that of surgery. Stereotactic radiosurgery requires an extensive...
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Time : 11 min 02
Added : 14/03/11 15:56
Tags: non small cell lung cancer stage / surgery for lung cancer / lung cancer
EMCTO 2011: Maintenance treatment for advanced non-small cell lung cancer
Prof Filippo de Marinis, Azienda Ospedaliera San Camillo Forlanini, Rome, Italy, talks about the current standard treatment options for patients with advanced non-small cell lung cancer (NSCLC) and explains how these patients may benefit from maintenance treatment. Prof de Marinis explains what maintenance therapy consists of, discusses how this can improve patient survival without increasing toxicity and outlines some clinical trials which are currently evaluating the efficacy of this...
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Time : 10 min 38
Added : 15/03/11 12:37
Tags: non small cell lung cancer treatment options / small cell lung cancer treatments / current treatments for lung cancer
ASCO 2010: Systemic therapy - what lies ahead?
Prof Jean-Charles Soria - Institut Gustave Roussy, Parris, France Dr Soria speaks about locally advanced non-small cell lung cancer and the importance of personalised therapy. The development of drugs such as crizotinib, which are successful at treating a specific subset of patients, is significantly increasing the effectiveness of lung cancer treatment. Dr discusses tumour samples and the size of the sample that should be removed, the possibility of combining targeted agents and the importance...
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Time : 6 min 15
Added : 28/07/10 09:25
Tags: locally advanced non small cell lung cancer / non small cell lung cancer treatment / small cell lung cancer treatments
EMCTO 2011: Optimal care for patients with stage I-III non-small cell lung cancer
Dr Paul van Shil, Antwerp University Hospital, Belgium, discusses surgery for patients with stage I-III non-small cell lung cancer. One of the primary surgical aims is to achieve a complete resection; this entails the complete removal of the primary tumour, a lymph node dissection, for all the resection margins to be free of tumour and for the highest mediastinal lymph node to be negative. TNM staging is used to decide whether the tumour should be treated with surgery or with chemotherapy; Dr...
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Time : 7 min 25
Added : 14/03/11 16:36
Tags: non small cell lung cancer stage / best hospital for lung cancer / surgery for lung cancer
AACR 2011: Combination therapy targeting MEK and PI3K pathways shows anti-tumour activity
Dr Johanna Bendell - Sarah Cannon Research Institute, Nashville, USA. The combination of two compounds that inhibit two of the most frequently mutated cancer pathways is showing promise in an ongoing Phase I trial. The research, presented by Dr Johanna Bendell, tests a combination of GDC-0973, which inhibits MEK1/2 and GDC-0941, which inhibits PI3K. The patients received a combination of different doses of GDC-0973 and GDC-0941; these drug combinations were well tolerated and only produced with...
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Time : 4 min
Added : 27/05/11 09:19
Tags: non small cell lung cancer treatment / small cell lung cancer treatments / targeted therapy for lung cancer